Frequently Asked Questions | GENESIS – 1000 Marina Life Science Space for Lease, Brisbane

GENESIS – 1000 Marina is located at 1000 Marina Boulevard, Brisbane, California 94005. The building sits at Sierra Point along the San Francisco Bay waterfront in northern San Mateo County, immediately adjacent to the South San Francisco life science cluster. It has direct on and off ramp access to US-101 and is approximately 6 miles south of downtown San Francisco (a 15-minute drive) and 9 miles north of San Francisco International Airport (a 10-minute drive).

GENESIS – 1000 Marina has direct on and off ramps to US-101, providing fast access throughout the Bay Area. The building is approximately 15 minutes from downtown San Francisco and 10 minutes from San Francisco International Airport (SFO). The Sierra Point location also offers commuter access for teams traveling from the Peninsula, the East Bay via the San Mateo Bridge, and the South Bay.

The Sierra Point Shuttle is a free service for tenants, connecting them to BART at the Balboa station (6.1 miles) and Caltrain at the Millbrae Transit Center (8.7 miles) during high-traffic morning and evening commute hours. Shuttles are partially funded by the Sierra Point Owners Association in association with the SF County Transportation Authority, Caltrain, SamTrans, BART, BAAQMD, and C/CAG.

Yes — direct access. The waterfront Bay Trail runs adjacent to the property. Tenants regularly use the trail for walks, runs, and breaks between bench time. It is one of the most differentiated features of the Sierra Point location.

Brisbane sits immediately adjacent to the South San Francisco life science cluster — the largest concentration of biotech tenants in the United States — without the cost basis or congestion of core South San Francisco submarkets. The Sierra Point location offers direct US-101 access, free shuttle service to BART and Caltrain, and a waterfront environment with direct Bay Trail access. Tenants benefit from proximity to South San Francisco's talent pool, CRO ecosystem, and vendor network, with shorter commutes from San Francisco and the Peninsula and a more efficient operating cost basis.

GENESIS – 1000 Marina is a six-story, ±114,000 RSF Class A office and laboratory building at Sierra Point in Brisbane, California. It is part of the GENESIS platform — Phase 3 Real Estate Partners' portfolio of science-ready environments designed for growth-stage life science companies. The building is purpose-built to accommodate small to mid-size suites, making it a natural home for Series A and B biotech teams scaling from early validation through expansion.

GENESIS – 1000 Marina is owned by Phase 3 Real Estate Partners (P3RE) in partnership with Bain Capital Real Estate. P3RE is the operating sponsor and asset manager; Bain Capital Real Estate is the institutional equity partner. P3RE has more than 30 years of experience in life science real estate, with approximately 5 million square feet across leading U.S. innovation clusters in San Francisco, San Diego, and Boston.

GENESIS – 1000 Marina is approximately 114,000 rentable square feet (RSF) across six stories. It is a Class A multi-tenant laboratory and office building designed for small to mid-size life science companies.

Full building MEP (mechanical, electrical, plumbing) infrastructure upgrades were completed in 2020. The lobby has been modernized, a new emergency generator is in place, and tenant hazmat and storage rooms have been added — alongside ongoing investment in shared amenities and the tenant experience.

GENESIS – 1000 Marina offers a range of lab and office suites from approximately 5,000 to 20,000 RSF — designed to accommodate growth-stage life science teams from Series A through Series B expansion. Suites are offered in two formats: Spec and Turnkey. Current availability varies; contact the leasing team for the latest inventory.

Spec suites are pre-built lab and office shells with full base infrastructure already in place — including BSL2-rated single-pass air, lab sinks with eyewash stations, fume hood capacity, and house air and vacuum distribution. Tenants bring their own furniture and equipment and customize finishes to their team's identity and workflow. Turnkey suites are fully built and fully furnished — workstations, conference rooms, huddle rooms, break areas, and IT closets are all in place. Furniture, fixtures, and select equipment are included so teams move in and start working without a construction or design phase.

Spec suites work best for teams with specific bench layout needs, existing furniture investments, or a clear identity they want to express in their space. Turnkey suites work best for teams at a critical inflection point — fresh capital, hiring quickly, or transitioning from incubator space — who cannot afford to lose time to buildout or furniture procurement. The leasing team helps tenants evaluate the right path based on timeline, capital priorities, and operational needs.

Turnkey means science-ready on day one. The lab is built, infrastructure is live, and furniture is in place. Teams move in, plug in their science, and start working — without a construction timeline, design phase, or delay between signed lease and productive bench time.

Timing depends on the offering. Turnkey suites can be operational within weeks of lease execution because the space is fully built and furnished. Spec suites are also operational quickly — base lab infrastructure is in place, so tenant work is limited to furniture, customization, and equipment installation. P3RE coordinates onboarding directly in both cases, so tenants are not managing multiple vendors at a critical inflection point.

Yes. Tours can be coordinated within days through the P3RE leasing team or CBRE. Both Spec and Turnkey suites can be toured ahead of occupancy.

Yes. Because GENESIS – 1000 Marina supports a range of suite sizes from approximately 5,000 to 20,000 RSF, tenants can pursue expansion within the same property as their team scales.

GENESIS – 1000 Marina supports BSL-2 laboratory operations with single-pass air.

GENESIS – 1000 Marina is biology and chemistry capable. Suites are built with single-pass air, lab sinks with eyewash stations, dedicated lab support rooms, chemical fume hood capacity, and house air and vacuum distribution. Specific configurations vary by suite — contact the leasing team for details on a specific space.

•         Full building MEP infrastructure upgrades completed in 2020

•         New emergency generator

•         Tenant hazmat and storage rooms

•         On-site shipping and receiving services

•         Tenant experience app for streamlined access and service requests

•         Surface & Covered Parking with EV chargers

Yes. The building includes dedicated tenant hazmat and storage rooms, with shipping and receiving services managed on-site.

The GENESIS Spec Lab Program is how P3RE delivers pre-built, science-ready lab suites across the portfolio. The program brings consistent base infrastructure — BSL2 capability, lab utilities, fume hood readiness — into every suite, enabling Series A and B biotech teams to move into purpose-built environments quickly without spending capital, time, or attention on ground-up construction. Both Spec and Turnkey offerings at GENESIS – 1000 Marina sit within this program.

•         On-site fitness center with showers and lockers

•         Common lounge with Wi-Fi

•         Outdoor lounge and picnic area with Wi-Fi

•         Shared conference spaces

•         Direct access to the waterfront Bay Trail

•         Free shuttle services to Caltrain and BART

•         (Adjacent Campus) fitGENESIS — state-of-the-art waterfront fitness facility

•         (Adjacent Campus) K+D Marketplace — daily lunch, catering, food program, and private event space

•         (Adjacent Campus) Up & Atom Coffee Co. — coffee and pastries on campus

Yes. In addition to conference and huddle spaces within individual suites, the building offers shared conference spaces available to all tenants — useful for board meetings, all-hands events, and visiting investor sessions.

Beyond K+D Marketplace and Up & Atom Coffee on campus, tenants have access to a wide range of restaurants, cafés, and amenities in South San Francisco and Brisbane — all within a short drive.

Yes. The building provides on-site shipping and receiving services managed directly by property operations, with dedicated tenant hazmat and storage rooms available within the building.

Yes. The tenant experience app streamlines access, service requests, building communications, and amenity bookings — designed to remove friction from the day-to-day.

It means having a real estate partner, not just a landlord. From the first tour through every growth milestone, P3RE shows up as a present, accountable operator. That looks like transparent deal structuring, leadership accessibility, and proactive engagement at key inflection points.

On-site property management runs the building day-to-day, supported by a dedicated team of engineers and a shipping and receiving operation — all aligned with ownership.

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GENESIS – 1000 Marina offers Class A life science infrastructure comparable to leading South San Francisco and Mission Bay buildings, with several distinct advantages: immediate adjacency to the South San Francisco biotech cluster, direct US-101 access, free shuttle service to BART and Caltrain, and a waterfront environment with direct Bay Trail access. The boutique scale (±114,000 RSF) and the Spec / Turnkey delivery options make it a strong alternative for growth-stage companies that want SSF-quality lab space and proximity.

GENESIS – 1000 Marina is designed for growth-stage life science companies — typically Series A through Series B biotechs — scaling from early validation through expansion. The suite range (approximately 5,000 to 20,000 RSF), the choice between Spec and Turnkey delivery, and the GENESIS Spec Lab Program's pre-built infrastructure align with companies that want purpose-built lab space without the construction timeline of ground-up tenant improvement. Contact for latest availability.

Contact the leasing team directly. From P3RE: Rebekah Studer, Vice President, Leasing & Marketing (951.663.2997, studer@p3re.com). From CBRE: Simon Clark (650.577.2938), Damon Schor (650.494.5121), or Alex Wilson (650.577.2923). Tours can be coordinated within days.

Visit P3RE.com for the full portfolio and platform overview.